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{bio,medical} informatics

Friday, January 13, 2006

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find related articles. powered by google. Baltimore Sun Genome pioneer reinvents itself

"Celera Genomics Group, the Rockville biotech that won international fame in the race to map the human genome with scientist J. Craig Venter at the helm, has again outlined plans to reinvent itself since those heady days in 2000.

Celera, a division of Applera Corp. of Conn., said yesterday that it will abandon internal drug development efforts to focus on discovering proteins for use by other drugmakers and on creating products to diagnose diseases, an area of recent revenue growth for it.

This will be Celera's fourth incarnation in its continuing quest for profitability."

redux [02.10.04]
find related articles. powered by google. Genomeweb Celera Pledges to Deposit Human Genome in GenBank, Release Assembler Source Code

"In a paper published in the Proceedings of the National Academy of Sciences, Celera Genomics has vowed to deposit the draft human genome sequence it published in 2001, as well as two more recent human genome assemblies, in GenBank.

The company also pledged to release the source code for its Celera Assembler genome assembly algorithm."

find related articles. powered by google. Genome News Network Celera Human Genome Sequence Will Be Public

"Their report, to be published online in the Proceedings of the National Academy of Sciences, compares the accuracy of the draft sequences against the "finished" human genome sequence now available at GenBank.

According to the report, both versions "covered about the same amount of the genome, but they did so in different ways." The Celera sequence provided "more order and orientation" while the HGP sequence provided "better coverage of exact and nearly exact repeats.""

redux [06.13.02]
find related articles. powered by google. The New Scientist Celera abandons gene sequencing

"But Celera's rival published its version free of charge on the internet, a move which damaged Celera's commercial prospects. "That has had an impact," says Bennett. "Any stand-alone information business will be challenged because the value of information degrades," he adds.

But he denies that the venture has been a failure. "We have 250 subscribers, both commercial and non-commercial," says Bennett. The business even makes a profit, but the company will not discuss the impact of the free genome data on profits."

redux [01.28.02]
find related articles. powered by google. The Washington Post Celera Changed, Venter Couldn't

"As all that was happening, people who know him say, White, Venter's boss, was getting grumpy. He well knew that Celera, under its original business plan, could not deliver long-range earnings growth that would justify what the market was paying for Celera shares. One top genetic scientist said White snapped to him in the midst of the publicity barrage, "'This is all nice, but we need a business plan.'"

They quickly came to the same conclusion as many minds before them: In biology and medicine, the only business plan that offers the potential of extraordinary profits is drug development. All the biotechnology superstars have been companies with hit drugs."

redux [01.22.01]
find related articles. powered by google. BBC News Genome pioneer steps down

"Dr Craig Venter, the US scientist who led the private effort to decode the human genome, has quit as boss of his company Celera Genomics."

""We are now at a critical juncture where my best contributions can be made in a scientific advisory role, allowing the rest of the organisation to continue Celera's progress toward becoming a successful pharmaceutical business.""

redux [06.09.00]
find related articles. powered by google. Forbes Celera's Worth Still Up In The Air

"Great discoveries do not necessarily make great businesses. Businesses have to sell something. Celera Genomics doesn't sell or make anything tangible. It hawks service and information. It sells access to lists of genes and computers that can sort through those messy lists. Samuel Broder, the company's executive vice president and chief medical officer, makes Celera sound like some kind of consulting company, or perhaps a library."

"Venter's quest could be a fable, with all sorts of morals about the power of capitalism and the importance of a single, brilliant, willful individual who used the market to shake the ivory towers of science. But those morals only hold if Celera succeeds, if business and science blend to propel the company into the future with breathtaking speed without rocketing it into the realities of the marketplace. Celera could become one of the great business success stories. It could also be a financial train wreck."

Right now, that makes it a very volatile stock."

redux [07.17.00]
find related articles. powered by google. BBC News Celera plans next step

"Craig Venter, head of Celera Genomics which last month completed the map of the human genome, has outlined his next goal.

Speaking at a conference he said his new task was to map the proteins which drive all chemical reactions in the body."

""A big part of the business is the straightforward providing of information, but I'm not complacent just to do that," Venter said."

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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