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{bio,medical} informatics

Thursday, December 08, 2005

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find related articles. powered by google. National Geographic News Dog Genome Mapped, Shows Similarities to Humans

"Scientists had previously found that about 5 percent of the human genome sequence appears in the mouse genome. The new study shows that 5 percent of the human genome is also shared with dogs.

Significantly, the sequences that are conserved in all three species are virtually the same.

"[This] indicates that there is a core set of noncoding sequences needed to make a mammal.""

redux [10.08.03]
find related articles. powered by google. Genomeweb Milk Bones and the Dog Genome: Illinois Researchers Digging For Answers

"Building on the newly finished draft of the dog genome, a team at the University of Illinois is conducting a study of the nexus between diet and gene expression in dogs, the University said today."

""Genome sequencing allows us to understand health across animals," Schook said in a statement. "Dogs, like humans, get diseases associated with lifestyles. Thus not exercising and over-eating can result in obesity and diabetes. Information about human diseases can be used to treat dogs, and understanding dog diseases can be used to treat humans.""

redux [09.29.03]
find related articles. powered by google. Nature: Science Update Dog genome unveiled

"The dog is the latest animal to have its genome sequenced. Shadow belongs to Craig Venter, the researcher whose privately funded project sequenced the human genome using his own DNA."

"The new sequence reveals that 18,473 dog genes have human equivalents. This already surpasses the 18,311 known from the mouse sequence. The team also found genes related to a dog's life: they have many more that are linked to smell than we do."

find related articles. powered by google. Genomeweb Venter & Fraser Publish 1.5X Sequence Coverage of Their Poodle

"The researchers assembled 6.22 million sequences of canine DNA for 1.5X coverage, or 78 percent, of the genome."

""In little more than a decade genomics has advanced greatly and we now have approximately 150 completed genomes, including the human, mouse and fruit fly, in the public domain," Craig Venter, president of TCAG and the J. Craig Venter Science Foundation, which paid for the dog genome research, said in the statement. "Our new method is an efficient and effective way of sequencing that will allow more organisms to be analyzed while still providing significant information.""

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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