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{bio,medical} informatics

Tuesday, July 15, 2003

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Wired Magazine The End of Cancer (As we Know it)

"Even now, researchers are split over just how complicated cancer will turn out to be in the end - and some argue that our growing understanding of its molecular biology may also reveal intractable new levels of complexity. (One example: Researchers at UCLA's Jonsson Cancer Center recently investigated how overexpression by the Her2 gene affected the behavior of other genes - and found more than 500 changes.) But for now, optimism still holds sway. And if we succeed, at long last, in charting a tumor's mysterious mechanisms, getting diagnosed with cancer in 2015 could be a distinctly different experience than it is today. Much as AIDS evolved from being a mysterious disease that killed healthy young men in six months to a mostly survivable condition, so cancer might become a manageable illness. "More like an annoying mole in your garden than an alien taking over your body," as one researcher puts it. Either way, Golub believes, students of biology 10 years from now won't be able to imagine a time when cancer was treated without a molecular understanding of how it works."

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“Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.”

BIOINFORMATICS IN THE 21st CENTURY

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