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{bio,medical} informatics

Thursday, June 27, 2002

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find related articles. powered by google. BioMedNet Seeing patterns in proteins
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"Now that sequencing the human genome is moving off the front page, advances in understanding protein structure and function are attracting more attention. The field has a new tool in TRILOGY, a computer program designed to identify patterns in the amino acid sequences of proteins. The programmers believe that TRILOGY will aid in the prediction of protein structure, the identification of novel motifs with functional or structural significance, and the annotation of recently determined structures. For some examples, see TRILOGY's Web site.

Reference: Bradley, P., Kim, P.S., and Berger, B. 2002. TRILOGY: Discovery of sequence-structure patterns across diverse proteins. Proc. Natl. Acad. Sci. U.S.A. 99(13):8500-8505."

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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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