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{bio,medical} informatics

Thursday, June 13, 2002

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"There are two theories surrounding the duplication of vertebrate genomes. The "big-bang mode" theory suggests that duplication occurred on a large-scale in the past. The "continuous mode" theory favors small-scale duplications. The accuracy of these two theories has significant implications for understanding vertebrate genome duplication. A recent extensive analysis of gene databases indicates "that large- and small-scale gene duplications both make a significant contribution during the early stage of vertebrate evolution . . ."

"Reference: Gu, X., Wang, Y., and Gu. J.. 2002. Age distribution of human gene families shows significant roles of both large- and small-scale duplications in vertebrate evolution. Nature Genet. 31(2):205-209.”

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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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