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{bio,medical} informatics

Tuesday, May 14, 2002

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Bio-IT World When “off-the-shelf” works just fine

"For small cash-strapped biotechs, off-the-shelf computers and databases represent an attractive five-figure option versus millions for supercomputers and Unix solutions that easily rocket into six figures.

“Off-the-shelf” — also known as commodity components — usually means the Windows operating system and applications running on Intel servers or workstations. Rosetta Genomics, a two-year-old Israeli company, is using 8-processor Dell servers, Microsoft SQL Server 2000, Windows 200 Data Center, and a finely tuned EMC CLARiiON storage system to mine two terabytes of genomic data, searching for patterns relevant to drug discovery and disease. Before the year is out, Rosetta promises that its database will grow to 10 TB."

redux [03.26.01]
Tim O'Reilly Business Computing Isn't Where The Action Is Going to Be
"The conjunction of hacker interest in science, the enormous commercial potential of genomics, proteomics and other bioinformatics disciplines, and the availability of cheaper supercomputing via distributed computation, seem to me to be an explosive mix."

"Every time we've had a radical lowering of the barriers of entry into a computing market, that market has exploded. The industry-standard IBM PC architecture liberated software developers from the need to work for hardware vendors; the open standards of the internet, plus the simplicity of HTML, and the power of scripting languages, allowed content providers to build the information applications that we now take for granted on the web. Now, hackers and scientists are working together to break down the barriers to discovery."

"Scientific computing is going to be where the action is."

redux [09.07.00]
ScienceDaily Supercomputers Help University Of Idaho Scientists Explore Genetics And Bioinformatics
"University of Idaho computer scientists and mathematicians are joining biologists to explore new ways to interpret the complex genetic information that describes all living things and their relationships.

Along the way, UI students returning to school this fall will find a new course few schools could hope to offer: building a new supercomputer."

"The students will work on every step of the project, from determining the requirements the supercomputer must meet, though the purchase, assembly, software selection and installation. "They are involved from start to finish. It should be a great experience for them," Heckendorn added." ""It's commodity computing. If you can only buy commodity computers and hook them together with the right stuff in the right way, you can get supercomputing power," he said. Although multi-million dollar specialty supercomputers still dominate the high end of the market, Beowulf-style supercomputers are gaining."

[ rhetoric ]

“Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.”

BIOINFORMATICS IN THE 21st CENTURY

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