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Thursday, September 06, 2001

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find related articles. powered by google. EyeForPharma Big pharma takes Entropia's distributed computing technology for a test drive

"As the pharmaceutical industry looks for new ways to increase productivity and capitalize on the growing number of new drug targets emerging thanks to the explosion in genomics data, a new and potentially powerful tool is emerging and catching the eye of many of R&D directors across the industry. Distributed computing is quickly becoming more than a "buzz word." In fact, it's becoming a reality at some of pharma's biggest companies."

""We're intrigued by the potential of grid computing technology," said Richard Vissa, Executive Director of Global Core Technologies, Informatics, at Bristol-Myers Squibb's Pharmaceutical Research Institute. "Even a PC network of modest size has the potential to deliver the computational power comparable to some of our large supercomputers. Given the number of PCs throughout our organization, we could see a significant increase in computing performance for certain applications..""

redux [08.29.01]
find related articles. powered by google. Nature: Science Update Parasite corrals computer power

"According to The Hitchhiker's Guide to the Galaxy, hyper-intelligent pan-dimensional beings (disguised as mice) are using us to compute The Ultimate Question of Life, The Universe, And Everything. Now earthling scientists have roped unsuspecting web servers into a similar - albeit slightly less ambitious - exercise in parasitic computing.

Using the Internet itself as a computer, Jay Brockman and colleagues at the University of Notre Dame, Indiana, have solved a mathematical problem with the unwitting assistance of machines in North America, Europe and Asia."

find related articles. powered by google. EyeForPharma Novartis evaluates Entropia's distributed computing technology for accelerating drug discovery

""The vast quantities of data involved in the genomic era of drug discovery are quickly outpacing advances in computing technology," said Robert North, Entropia CEO. "Distributed computing allows companies to cost-effectively access the massive computing power they'll need by using their existing PC networks. It's quite exciting that companies like Novartis are deploying our platform to demonstrate the potential of distributed computing as a valuable tool in drug discovery efforts.""

redux [07.22.00]
find related articles. powered by google. The Standard Distributed Computing Goes Commercial

"The distributed-computing model could be one of those rare cases where capitalism and pure scientific research mesh. Not every lab can afford to pay $200,000 for an eight-processor Origin 2000 SGI supercomputer, much less $1 million for a 40-processor machine, says David Fenstermacher, director of scientific computing for the medical school at the University of North Carolina at Chapel Hill. (Fenstermacher is also acting director of the campus' Center for Bioinformatics and a United Devices adviser.) And even the most powerful supercomputers need time to process data.

A project that would take several months on a supercomputer - creating a 3D model of a protein's linear be accomplished in much less time using thousands of distributed computers"

redux [02.18.01]
find related articles. powered by google. Wired News Genome Effort Hits Home

"A new distributed computing project is comparing gene data with protein structures to determine their genome sequences.

"Genome@home is the second project from Stanford University's chemistry department, which also runs the Folding@Home project.

"Whereas Folding@Home is designed to learn how genomes fold into proteins, Genome@Home was launched this week to try and reverse engineer known proteins by guessing the genome sequence of their structures."

redux [10.09.00]
find related articles. powered by google. ACM CrossRoads The SETI@Home Problem

"The SETI@Home problem can be thought of as a special case of the distributed computation verification problem: "given a large amount of computation divided among many computers, how can malicious participating computers be prevented from doing damage?" This is not a new problem. Distributed computation is a venerable research topic, and the idea of "selling spare CPU cycles" has been a science fiction fixture for years."

"The Internet makes it possible for computation to be distributed to many more machines. However, distributing computing around the internet requires developers to consider the possibility of malicious clients."

"The general study of secure multiparty computation has produced much interesting work over the last two decades. Less well studied, unfortunately, are the tools and techniques required to move the theoretical results to the real world. The old dream of massively distributed computations is finally coming true, and yet our tools for building and analysing real systems still seem primitive. The challenge of the next few years will be to bridge this gap."

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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