snowdeal logo

archives archives

{bio,medical} informatics

Saturday, April 28, 2001

bookmark: connotea :: ::digg ::furl ::reddit ::yahoo::

find related articles. powered by google. GenomeWeb Experts Question Value of Myriad's Proteome Mapping Strategy
"Myriad Genetics made a splash earlier this month when it announced a collaboration with Hitachi and Oracle to "map the human proteome" by 2004.

The scope of this ambitious task could vary widely, depending on how the companies want to define "map" and how thorough they want to be. But regardless of how Myriad and its collaborators define the outer limits of the project, proteomics experts are questioning how much scientific value there is Myriad's basic approach.

These scientists say Myriad's two pronged attack on the proteome, an automated yeast two-hybrid strategy combined with MALDI-TOF mass mass spectroscopy analysis of protein complexes, won' t provide Myriad and its partners with a thorough understanding of how proteins play a role in disease."
redux [03.31.01]
find related articles. powered by google. The Scientist Is a Human Proteome Project Next?
[requires 'free' registration]
"A commonly expressed opinion is that a single Human Proteome Project can never match HGP's success. Eric S. Lander , director of the Whitehead Center for Genome Research in Cambridge, Mass., notes that biologists simply don't know how to characterize the proteome "from end to end, nailing every protein. The tools are not ready. And it's not clear that [such a project] makes sense." He contrasts proteomics to HGP where "there is a certain fixed number of base pairs--about three billion--and we were going to get them all. And so it had a beginning and an end to it."

redux [01.31.01]
find related articles. powered by google. GenomeWeb Proteomics Effort Shouldn't Mimic Genome Project, Experts Say
"Can sequencing do for the proteome what it did for the genome?

On Wednesday, a number of world-renowned researchers in the field of proteomics issued a resounding " no."

Instead of devoting their efforts to decoding the human proteome, proteomics researchers should focus on developing a larger picture of protein structure, function, and pathways within cells and organisms, panelists said at a New York Academy of Sciences briefing entitled "The Promise of Proteomics."

"When a company has phenomenal success with strategy A, you want to do strategy A on the next subject," said John Richards, a professor of organic and biochemistry at California Institute of Technology, referring to current corporate attempts to map the proteome.

"This doesn't work," he said."

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


[ search ]

[ outbound ]

biospace / genomeweb / bio-it world / scitechdaily / biomedcentral / the panda's thumb / / nodalpoint / flags and lollipops / on genetics / a bioinformatics blog / andrew dalke / the struggling grad student / in the pipeline / gene expression / free association / pharyngula / the personal genome / genetics and public health blog / the medical informatics weblog / linuxmednews / nanodot / complexity digest /

eyeforpharma /

nsu / nyt science / bbc scitech / newshub / biology news net /

informatics review / stanford / bmj info in practice / bmj info in practice /

[ schwag ]

look snazzy and support the site at the same time by buying some snowdeal schwag !

[ et cetera ]

valid xhtml 1.0?

This site designed by
Eric C. Snowdeal III .
© 2000-2005