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{bio,medical} informatics


Monday, January 08, 2001

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find related articles. powered by google. The Nando Times Biologist says germs, not genes, to blame for most human ailments
"Some of Paul W. Ewald's best thinking started with an attack of diarrhea on a field trip to Kansas.

A zoologist, he was studying the social habits of sparrows. But during that ordeal 24 years ago, he had time to ponder other things: Was his personal predicament simply the havoc of a germ bent on spreading itself around? Or was his body trying to flush away the germ? Was this the evolutionary adaptation of an invader or the evolved human defense against it?

Healthy again, he checked the medical literature. "I realized that virtually all considerations of evolutionary processes in the medical literature were incorrect," he says."
redux [07.13.00]
find related articles. powered by google. The New York Times Genes May Cause 25% of 3 Major Cancers
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"Genes may cause more than one-quarter of three major types of cancer, more than previously thought, a group of researchers says.

Scandinavian researchers concluded that genes account for 42 percent of the risk for prostate cancer, 35 percent for colorectal cancer and 27 percent for breast cancer.

The rest of the cases are caused by what people do, such as smoking and diet, or what happens to them, such as on-the-job hazards or viral infections, the researchers said."

"...the conclusion runs contrary to the widespread belief that scientists "will find solutions or cures to all diseases in the genes," Dr. Lichtenstein said. "That won't be the case."

redux [04.25.00]
find related articles. powered by google. UniSci Selfish Gene Theory Of Evolution Called Fatally Flawed
"In the current issue of Advances in Complex Systems (February-April), Dr. Yaneer Bar-Yam, president of the New England Complex Systems Institute and an expert on the application of mathematical analysis to complex systems, contends that the selfish-gene theory of evolution is fatally flawed.

If his mathematical proof gains general acceptance, it will shut the door on controversial "gene-centered" views of evolution.

Bar-Yam, in the upcoming article, proves that the "selfish gene" approach is not valid in the general case. He demonstrates that the gene-centered view, expressed in mathematical form, is only an approximation of the dynamics actually at work."

"The key to Bar-Yam's analysis lies in recognizing three levels of structure in nature: the gene, the organism and the group (or network) of organisms."


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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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