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{bio,medical} informatics


Thursday, September 21, 2000

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find related articles. powered by google. Wired News Brother, Can You Spare a DNA?
"A genetics company is beginning its first studies less than two months after launching an effort to recruit volunteers via the Internet to donate their DNA for experiments.

DNA Sciences has persuaded 4,500 people to give up a little of their genetic code for the greater good of science, which gives them enough samples to begin to search for the genetic causes of asthma, breast cancer and colon cancer."

"The researchers at DNA Sciences hope to help herald the much-hyped "age of personalized medicine." By studying variations in individuals' genes called "single nucleotide polymorphisms," or SNPs (pronounced snips), scientists say they will be able to determine who might be more susceptible to disease, and how people will react to certain drugs."
redux [09.02.00]
find related articles. powered by google. NPR : All Things Considered Tissue Banks
"Robert talks with Barry Eisenstein M.D., Vice President of Science and Technology for Beth Israel Deaconess Medical Center, and Professor of Medicine at Harvard Medical School, about his hospital's participation in creating an international tissue bank. They will be asking patients for permission to sell tissue left over from surgery. The tissue will be used by scientists worldwide for genetic research.”

redux [05.15.00]
find related articles. powered by google. The New York Times Who Owns Your Genes?
[requires 'free' registration]
""I just wanted to do something good," Mr. Fuchs said. "But once money came into the picture, why not have it be shared with me?"

These days more and more patients are asking the same question. Laboratories offer tests for more than 700 human genes, with more being discovered almost daily. And, for almost every gene, some medical institution or some company owns a patent on its use.

"The value of patients' tissues has potentially gone up enormously," said Dr. Barry Eisenstein, the vice president for science and technology at the Beth Israel Deaconess Medical Center in Boston. But, Dr. Eisenstein said, patients whose cells provided the genes that have been patented are almost never compensated. "

redux [08.24.00]
find related articles. powered by google. CBSMarketWatch Incyte's president named chairman
"The company also announced that Scott is forming a new online health company that will use the genetic information supplied by Incyte's technology and databases for public, procedural and research applications.

The company will link individuals to genomic information regarding their disease in order to reach understanding of a particular condition and enable individual participation in the search for remedy."

redux [08.01.00]
find related articles. powered by google. The New York Times Company Seeking Donors of DNA for a 'Gene Trust'
[requires 'free' registration]
"Wanted: your genes.

A California start-up called DNA Sciences is introducing a Web site today that will recruit people to donate their DNA to help find genes that cause disease. The company, which has James D. Watson, a discoverer of the DNA double helix, as a director and James H. Clark, Netscape's founder, as an investor, hopes to get 50,000 to 100,000 people to contribute to its "gene trust" by appealing to their altruism."

"Under DNA Sciences' program, volunteers answer on-line questionnaires about their medical history, and their family's. The company will then send someone to their homes or offices to collect blood samples. Healtheon/WebMD, the medical Web site, owns a stake in DNA Sciences and will be used to help recruit patients.

Donors will not be paid, as is true with the other companies as well."

redux [08.14.00]
find related articles. powered by google. Bioinform DNA Sciences Develops Two New Bioinformatics Tools for Genotyping
"LAST WEEK DNA Sciences announced plans to become a major force in the genomics sector by establishing a facility that will eventually identify one million genotypes a day. The company, which is backed by such industry icons and financiers as James Watson, Jim Clark, and George Soros, plans to use the information it generates from the 50,000 to 100,000 DNA donors it hopes to enlist to create better diagnostic methodologies.

But the Mountain View, Calif., upstart won’t be doing any of this with prepackaged bioinformatics tools. Instead, DNA Sciences will store, manage, and mine SNP data using software the company has developed in-house.

“You cannot buy off-the-shelf software that solves these problems and I think every company that does genetics has built their own software,” said DNA Sciences’ CEO Hugh Rienhoff."



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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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