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{bio,medical} informatics

Tuesday, April 04, 2000

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Tools: The GeneMine Project
"GeneMine is a free sequence analysis and visualization program that makes full use of analysis servers across the Internet, to automate your sequence analysis needs and filter for meaningful results. GeneMine summarizes these results as graphical annotations on your sequence alignment, in a form that can be conveniently browsed, analyzed further, saved, and even published as web pages or presentations."

"GeneMine is the third generation of the commercial sequence/structure analysis and modeling package LOOK from Molecular Applications Group (now part of Celera). Developed by Dr. Christopher Lee, LOOK/GeneMine have been widely used in the pharmaceutical industry and academia from 1994 to the present for both modeling and gene functional analysis. This package includes modeling software developed by Dr. Michael Levitt of Stanford (SEGMOD, homology modeling) and Dr. Lee (CARA, mutant modeling).

Dr. Lee joined the faculty of the UCLA Department of Chemistry in 1998, and persuaded MAG to allow UCLA to distribute the GeneMine software free to non-commercial users beginning January 2000.

The GeneMine source code is now being actively developed at UCLA under the auspices of the GeneMine Project. Our goal is to make GeneMine the most useful tool for analyzing gene function and features for scientists around the world! "

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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