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Friday, April 21, 2000

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Science Modeling Population Genetics
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"Population genetics relies heavily on mathematical modeling to make quantitative predictions about the behavior of genes in populations. These models are based on the principles of classic Mendelian gene inheritance; the Hardy-Weinberg equilibrium law, which predicts the gene frequency in a population; and Darwin's theory of natural selection.

"PopGene version 1 is a simulation program that explores the parameters that affect the behavior of alternative forms of a gene (alleles) in a population. The program window is composed of three smaller windows specifying the parameters used, the calculated allele frequencies through each generation, and the graphical output of the calculations."

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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