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Wednesday, May 03, 2006

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find related articles. powered by google. Duke University Key Root-Development Pathway Mapped Using Advanced Genomic Technique

"Biologists have vastly expanded understanding of the biological machinery controlling the intricate process by which plant roots burgeon from single cells into complex tissues. A Duke University-led team's discovery of new components of the root-development pathway in the mustard plant, Arabidopsis thaliana, represents both a scientific and technical achievement, the scientists said."

"Technically, the genomic analytical method they used also will offer biologists a highly useful approach to discovering the components of complex biological pathways governing development, the researchers said. Their statistical "meta-analysis" technique involved using computational methods to integrate data from multiple genetic analyses using several DNA microarrays -- popularly known as "gene chips." Each of these chips contained some 24,000 genes representing nearly the entire genome of the Arabidopsis plant."



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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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