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{bio,medical} informatics


Tuesday, May 25, 2004

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find related articles. powered by google. Bio-ITWorld Opinion: Grid Not Ready for Prime Time

"Grid computing is no empty buzz phrase. In fact, it's a very substantial approach for scaling and optimizing distributed hardware resources. Grids aggregate idle processor cycles, storage capacity and other resources throughout networks, thereby serving client applications with supercomputer-grade performance. Depending on how broadly they're implemented, grids can extend dynamic resource brokering, parallel processing and load balancing to all computers on an intranet, extranet and even a portion of the Internet."

"So grid is starting to mature, as a market and an approach for distributed processing. But the road to maturity is long, and grid computing won't be ready for enterprise prime time for at least another three to five years."

redux [04.26.04]
find related articles. powered by google. Bio-ITWorld The Changing Politics of Grid

"Last year we did a study on the market and asked some 50-plus multibillion-dollar corporations, the CIOs and others, about the issues or barriers to grid computing. One of the biggest barriers that we discovered was that there is a group of what we call non-technical issues related to grid computing, and effectively that turned out to be organizational issues or what we described as "the politics" of grid. The issue there is really that people are unwilling to share their resources."

In the case of politics, then, what happens is most people feel -- and this came out in our study last year and again this year -- is that the politics are a significant issue."

redux [03.19.04]
find related articles. powered by google. News.Com Grid projects hunt for new cures

"The humble personal computer used to send e-mail or surf the Internet could quietly be finding a way to stop cancer, treat smallpox or counter a bio-terror attack with anthrax spores."

Novartis is among the growing number of drug makers using in-house grids to search for new drugs. It has 2,700 PCs linked up now and aims to boost that to between 20,000 and 25,000 within two years, said Manuel Peitsch, the head of informatics and knowledge management at its drug research labs."

redux [11.29.03]
find related articles. powered by google. The Scientist High-Performance Computing On-Demand
[requires 'free' registration]

"Various software packages are designed to build and manage internal grids using an enterprise's own computing resources, the market leader being Grid MP(TM) from United Devices of Austin, Texas.

Such solutions may be robust and help mop up otherwise wasted computing resources, but they still require considerable expertise to run efficiently and ensure that jobs are scheduled correctly and meet agreed priorities. The major cost of a grid lies in managing the resources rather than in the hardware itself, says Atkinson. Therefore, the cost saved by utilizing spare computing resources may be more than outweighed by the cost of additional IT staff. For this reason alone, Atkinson expects many laboratories will make use of external grids."

redux [10.01.03]
find related articles. powered by google. Bio-IT World Volunteer Grid Tackles Smallpox Research

"Using the computing power of 2.5 million PCs donated by volunteers from around the world, researchers have narrowed the search for a new treatment for smallpox, now seen as a possible terrorist weapon, to 44 drug molecules that may render the smallpox protein inactive.

The volunteered computing power, set up in a grid through grid.org, contributed more than 250,000 years of computing time in the eight-month Smallpox Research Grid Project, project leaders said. "

find related articles. powered by google. Government Computer News Grid computing project hones smallpox research

""When this project was first explained to me, I thought it was rather Jules Verne-ish," said Army Brig. Gen. Patricia L. Nilo, acting deputy assistant for chemical and biological defense."

Collectively, the 2.5 million PCs running the grid screensaver constituted the world's largest supercomputer, said Todd S. Ramsey, IBM Corp.'s general manager for global government industry."

redux [07.17.03]
find related articles. powered by google. Bio-IT World Congress Questions US Supercomputing Efforts

"The U.S. is falling behind Japan in the area of supercomputing, as federal research agencies have shifted their focus toward grid computing in the past decade, according to witnesses at a congressional hearing Wednesday.

The result is that U.S. companies have less access to supercomputing resources because demand from the U.S. government has traditionally driven the supercomputing industry in the U.S., critics of the government's efforts in high-performance computing told the U.S. House Science Committee."

redux [06.28.03]
find related articles. powered by google. Bio-IT World Marketing hijacks everything, grid developers told

""The language really matters, and confusion on language can be really damaging," Gage said. Citing Sun's experience with Java as an example, he warned developers about the dangers of hype and cautioned them that grid computing risks becoming a catch-all phrase that promises more than it ever can deliver."

"The term has been used to describe a myriad of computing scenarios, from harnessing the processing power in networked PCs build a vast, distributed "supercomputer," to an alternative architecture for the Internet that will provide the underpinnings for Web services and other distributed applications."

redux [05.21.03]
find related articles. powered by google. eWeek Gateway Grid Used in Diabetes Research

" The American Diabetes Association is using Gateway Inc.'s grid program to run a compute-intensive application designed to accelerate diabetes-related research.

The association, based in Alexandria, Va., is running the Archimedes software application, which Richard Kahn, chief scientific and medical officer for the ADA, called "the Sims City of health care." Using the program, the association can create an environment with any number of variables--such as doctors, hospitals, rooms, costs, patients and treatments--and run numerous what-if scenarios as a way of researching multiple aspects of diabetes care and running clinical studies."

redux [01.09.03]
find related articles. powered by google. Bio-IT World Grids: When Concepts Collide

"Clearly, grid computing means different things to different people, often at different times. To its most visionary pundits, grids symbolize the penultimate step in the evolution of computing architecture into a universal source of pervasive, utility-like computing power that companies can purchase as needed, much as they purchase electricity today. Most stalwart advocates believe that grids not only represent the IT environment of the future but also will ultimately eclipse in significance what the Internet is today."

"All hype aside, it is unlikely that grids will fundamentally change the way that scientific and technical computing is done in the near term, particularly in the private sector."

redux [09.13.02]
find related articles. powered by google. Genomeweb Pharma Eases onto the Grid, but Desktop Deals Highlight Remaining Obstacles

"A final obstacle that Stuart pointed out is of the self-inflicted variety: Grid, distributed, peer-to-peer, and other similar incarnations have become victims of their own hype. Increasing media coverage of these technologies has led to confusion in the marketplace, Stuart posited, "and when a prospect becomes confused, the easiest thing is not to do anything.""

"However, he added, there is a bright side to the publicity deluge. Citing the Gartner Group's annual "Hype Cycle of Emerging Technologies" report, which tracks new methods from the initial "tech trigger" period through the "peak of inflated expectations," the "trough of disillusionment," the "slope of enlightenment," and onto the final "plateau of productivity," Stuart noted that desktop grid computing might be working its way from the trough to the slope phase right now, largely because users are discovering which applications work best with the architecture."



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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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