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Nature: Science Update
Playing tag with the genome
"A new technique should aid the hunt for genes in the human genome sequence. The method, which tracks only switched-on genes in cells, will help researchers to distinguish between diseased and normal tissues, and could point the way to new treatments.
Andrew Simpson, of the Ludwig Institute for Cancer Research in Sao Paulo, Brazil, and colleagues have produced a whopping 700,000 DNA tags, representing the genes that are active in 24 normal and cancerous tissues."
[requires 'free' registration]
"Geneticists in Brazil who have devised a short-cut for decoding the human genome have made a "serious" contribution to the international effort, according to one of the field's leading analysts. The work represents "a significant contribution by people outside the mainstream US/UK axis," said Ian Hubbard, head of the human genome analysis group at the Sanger Center in the UK."
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“Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.”
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