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Wednesday, July 18, 2001

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find related articles. powered by google. BioMedNet For haplotype mappers, deja vu all over again
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"A US government-centered effort to gain useful information from a map of single nucleotype polymorphisms (SNPs) might be late off the starting block, again chasing a private effort toward the same goal. That conclusion is emerging even as the National Human Genome Research Institute (NHGRI) convenes a two-day planning meeting here, involving the SNP consortium of pharmaceutical and biotechnology companies as well as academic leaders."

"Larry Thompson, chief of the communications and public liaison branch of NHGRI, told BioMedNet News that there is no Haplotype Project currently underway, and this week's meeting (which Brooks had billed as the "Haplotype Meeting") will examine the opportunities that the science presents. "This is a natural extension of efforts that are currently underway and which we believe will help identify genes and their relationship to disease," he said. "How this project will take shape is a big unknown at the moment.""

find related articles. powered by google. Wired News Geneticists Await Haplotype Map

"An effort called the SNP Consortium is also underway to identify and interpret individual variations. Looking at SNPs individually can help determine predisposition to disease and potential reactions to drugs."

""It's like the differences between buses and cars," Venter explained."

"These are difficult concepts for non-scientists to understand, but Collins said everyone has an interest in knowing about this type of research."

""Trust me, it's going to be a very powerful way to understand genetic disease," he said."

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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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