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{bio,medical} informatics


Wednesday, February 28, 2001

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find related articles. powered by google. PENN Database Research Group K2/Kleisli and GUS: Experiments in integrated access to genomic data sources
"The integration of heterogeneous data sources and software systems is a major issue in the biomedical community and several approaches have been explored: linking databases, ``on-the-fly'' integration through views, and integration through warehousing. In this paper we report on our experiences with two systems that were developed at the University of Pennsylvania: an integration system called K2, which has primarily been used to provide views over multiple external data sources and software systems; and a data warehouse called GUS which downloads, cleans, integrates and annotates data from multiple external data sources. Although the view and warehouse approaches each have their advantages, there is no clear ``winner''. Therefore, users must consider how the data is to be used, what the performance guarantees must be, and how much programmer time and expertise is available to choose the best strategy for a particular application. Our experiences also point to some practical tips on how updates should be published by the community, and how XML can be used to facilitate the processing of updates in a warehousing environment."
redux [01.17.01]
find related articles. powered by google. The Collection of Computer Science Bibliographies Bibliography on Mediation, Database Integration, Database Interoperability and related topics
"personal bibliography on query mediation, database integration, database interoperability and related topics, concentrating on projects in genomic research. "


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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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