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{bio,medical} informatics


Monday, January 22, 2001

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find related articles. powered by google. Laboratory Network New platform for integrating heterogeneous bioinformatic tools
"The National Center for Genome Resources (NCGR; Santa Fe, NM) has released a version of ISYS, a new platform to integrate heterogeneous bioinformatics software tools and databases. The software can be easily downloaded and installed from the NCGR website and offers most of the functionality planned for the full users' release later this spring."

"The ISYS platform achieves integration not by integrating the data per se, but by integrating the applications that retrieve, display, and analyze the data. This, the develops say, is based on their observation that it is the experts themselves—those in gene expression research, gene ontology classifications, sequence alignment algorithms, etc.—who know best how to put their data in context. Putting data into context is an important step in transforming mere information into knowledge."
find related articles. powered by google. NCGR ISYS: A Platform for Integration
"Integrating heterogeneous bioinformatics resources is difficult because the field is decentralized and moving rapidly. Many developers do not perceive an incentive to adhere to nascent standards sufficient to outweigh the cost of constrained development. Agreeing on standards is time-consuming and difficult (some even suggest futile). In the absence of global standards, most groups are trying to achieve integration by building their own "enterprise-wide" integrated systems from scratch, with web-based solutions that rely on networks of hypertext links, or with cross-database query systems that rely on complicated schema-mapping techniques . Each of these approaches has significant disadvantages. Large-scale, de novo development is slow and expensive, and can result in systems that are extinct before they are completed. Web-based solutions are severely limited by the user-interface capabilities of web browsers, and are ineffective for integrating local data with remote data. Cross-database query solutions make an unnecessary separation between data integration and software integration, and sometimes over-emphasize the importance of complex declarative queries..."

"We believe that ISYS represents a fundamentally different approach to the problem."


[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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