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The New Scientist Gene collection
"Britain's largest ever DNA collection project has been announced by the Medical Research Council. Genetic material from thousands of sick people will be collected and stored in databases across Britain."
""Perhaps the most ambitious is the colorectal cancer project in Scotland," says Rawle. "They're planning on taking samples from every person with colorectal cancer in Britain - that's a tremendous challenge."
Ellen Solomon at King's College London will lead a DNA breast cancer project. Mutations in single genes cause some cases of breast cancer, but most probably involve mutations in many genes, says Solomon.
Her team will take DNA samples from families with only slightly more cases of breast cancer than most. This suggests that they have a genetic predisposition to breast cancer, but that predisposition involves mutations in more than just one or two genes."
BioMedNet Here come the lawyers
[requires 'free' registration]
"In 1993, a researcher at the Miami Children's Hospital, with the encouragement and help of families of victims, discovered the genetic basis for Canavan disease, a disease of the central nervous system that affects 1 in 6,400 Ashkenazi Jews. The mutation, on chromosome 17, was patented, and the researcher developed a genetic test. Four parents and three nonprofit groups filed a lawsuit in a Chicago federal court claiming "misappropriation of trade secrets," because they used children's blood and tissue without consent to file the patent.
Reference: Marshall, E. 2000. Families sue hospital, scientist for control of Canavan gene. Science 290(5494):1062."
“Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.”
BIOINFORMATICS IN THE 21st CENTURY
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