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{bio,medical} informatics

Thursday, October 26, 2000

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find related articles. powered by google. BioMedNet Advanced genomics promise fruit fly exposure
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"According to Gos Micklam, a bioinformatics expert who joined the group from industry last year, "Drosophila is a terrific model organism to work on." Despite its complexity, he notes, the fly has only twice as many genes as yeast. It is also backed by huge research interest worldwide that goes back a century or more, which has produced detailed phenotypic data.

In particular however, he draws a distinction between "deterministic" and "algorithmic" developmental mechanisms. For instance, he says, those mechanisms that create the nematode, Caenorhabditis elegans, are deterministic in that the fate of every cell is more or less pre-determined and specified from the start. But Drosophila's mechanisms are algorithmic, he notes; the cells do not have a fixed lineage, and their developmental fate is partly the result of communication between cells.

The task of integrating the huge amounts of data to produce a comprehensive profile of gene expression, which Micklam describes as "the real challenge of genomics," will take many years, he says."
find related articles. powered by google. Wired News Genetic Data Glut Looms
"The Human Genome Project has amounted to piles and piles of information so far.

Scientists convened at the BioSilico 2000 conference here Thursday morning to talk about the best ways to make those piles useful."

""It's not who's got the best technology, but who knows best how to share the information," [Friedrick von Bohlen, chairman and CEO of LionBioscience] said."

redux [09.20.00]
find related articles. powered by google. BioMedCentral Freedom of Information Conference: The impact of open access on biomedical research
"How should biomedical research be communicated? How should research be assessed and validated?"

"Below are abstracts, transcripts, and biographies from the conference. Some presentations did not lend themselves to transcription. Where possible we have supplemented them with editorials from the speakers.

We have also commissioned editorial articles from several speakers and delagates at the meeting.

All thoughts, comments, and suggestions are welcome on our email discussion list"

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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