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Wednesday, July 12, 2000

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Discovery.Com Push To Find Disease Genes Begins
"Now that the human genome is almost completely mapped, research organizations are starting a major push to find the genes that cause human disease.

The National Human Genome Research Institute announced Tuesday that three academic centers will start work to find segments in the human gene structure that vary from person to person, a major step toward finding genes that cause heart disease, diabetes and other common diseases."
Wired Gene Projects Join Forces
"The researchers will isolate two million DNA fragments from the human genome and determine the sequence -- the order of the chemical letters A, C, T, and G -- of approximately 500 base pairs of the chemical letters.

The scientists then will compare the sequences they come up with to human genome DNA sequences already in the publicly available database of human genome sequence information called GenBank. "

"The researchers said the data will be made publicly available without restrictions on their use, consistent with the current data release policies of the Human Genome Project and the SNP Consortium.

However, they also said the SNP Consortium will file provisional patent applications on newly identified and mapped SNPs, but only to establish the dates of discovery. According to a press release, "no patents will be allowed to issue, keeping the data freely available for the unrestricted use of researchers worldwide." "


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Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.

BIOINFORMATICS IN THE 21st CENTURY

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