{bio,medical} informatics
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""Plastics." When a family friend whispered this word to Dustin Hoffman's character in the 1967 film The Graduate, he was advocating not just a novel career choice but an entirely different way of life. If that movie were made today, in the age of the deciphering of the human genome, the magic word might well be "bioinformatics.""
"Corporate and government-led scientists have already compiled the three gigabytes of paired A's, C's, T's and G's that spell out the human genetic code--a quantity of information that could fill more than 2,000 standard computer diskettes. But that is just the initial trickle of the flood of information to be tapped from the human genome. Researchers are generating gigantic databases containing the details of when and in which tissues of the body various genes are turned on, the shapes of the proteins the genes encode, how the proteins interact with one another and the role those interactions play in disease. Add to the mix the data pouring in about the genomes of so-called model organisms such as fruit flies and mice, and you have what Gene Myers, Jr., vice president of informatics research at Celera Genomics in Rockville, Md., calls "a tsunami of information." The new discipline of bioinformatics--a marriage between computer science and biology--seeks to make sense of it all. In so doing, it is destined to change the face of biomedicine.
"For the next two to three years, the amount of information will be phenomenal, and everyone will be overwhelmed by it," Myers predicts. "The race and competition will be who can mine it best. There will be such a wealth of riches.""
Oscar Gruss & Son Trends in Commercial Bioinformatics
""The purpose of this document is to provide an overview of the rpidly emerging field of "commercial bioinformatics."
"For the purposes of this review, we define bioinformatics as the backbone computational tools and databases that support genomic and related research, which broadly encompasses the study of DNA structure/function, gene expression and protein production/structure/function.""
redux [05.10.00]
Alfred P. Sloan Foundation Hiring Patterns Experienced by Students Enrolled in Bioinformatics/Computational Biology Programs
"As expected, salaries for the most part climb as the level of training rises, starting in the $40,000-$50,000 range for BAs and reaching over $100,000 for one post doc. But there are exceptions. For example, two of the three undergraduates who were placed received salaries between $50,0000 to $60,000. This is higher than that earned by seven of the masters students, although ten of the nineteen masters students for whom we have salary information earn more than $60,000. One masters student received a starting salary of over $100,000. Reported salaries for five hires at the doctorate level are over $70,000. One is between $80,000 to $90,000; another is over $100,000; yet another is between $60,000 to $70,000. Three post docs received placements with a salary between $80,000 to $90,000. One post doc was placed at a salary of over $100,000. One institution reported that one or more masters student(s) received a signing bonus.""The results of our current survey make it clear that the majority of these jobs are not being filled by graduates of formal programs—who by our count represent about 15 percent of the positions advertised in 1997. And, we believe the 15 percent figure to be an overestimate given that ads have been growing over time and our most recent ad count is for 1997, a year earlier than our hiring data. This leads us to infer that most of the advertised positions are being filled by individuals trained in informal programs and by individuals who change jobs. The distinct possibility exists that a number of these jobs remain vacant for a period of time, an issue not studied here. Furthermore, our pipeline estimates (see Table 2) lead us to conclude that the number of individuals currently enrolled in formal programs falls far short of the number of positions that have recently been advertised."
[ rhetoric ]
“Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.”
BIOINFORMATICS IN THE 21st CENTURY[ search ]
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