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Sunday, May 07, 2000

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Bioinform Academic-Industry Initiative Will Develop Bioinformatics Tools to Model Living Cell
"A team of researchers led by Bob Franza of the University of Washington here is developing bioinformatics tools to create a quantitative model of the living cell.

The Cell Systems Initiative was launched late last year, and thus far has attracted the support of two corporate backers who would like to mine the data it generates to identify new drug targets."

"The goal, according to Franza, is to understand the stages of a cell's development. "How does one stage know when it's supposed to start and stop?" Franza asked. "How do we reconstruct the temporal process?" A complete model of the living cell will need to be understood not as parts, but as components of a continuous system, he said. To that end, the initiative also aims to build a computational infrastructure that can manage the entire dynamic system of data collection and integration."

Cellworks Project Information management and data analysis systems for the research biologist
"The Cellworks Project [referred to as CWP throughout this section] is a multifaceted design, research and development effort located in the Department of Molecular Biotechnology at the University of Washington. CWP is a combined basic biology research program and information systems research and development program focused on bringing the power and technologies available in today's computer industry to the biology research laboratory environment. The primary goal of the information systems research component of CWP is to develop an optimal networked environment for collaborating, distributed groups of biologists."

[ rhetoric ]

Bioinformatics will be at the core of biology in the 21st century. In fields ranging from structural biology to genomics to biomedical imaging, ready access to data and analytical tools are fundamentally changing the way investigators in the life sciences conduct research and approach problems. Complex, computationally intensive biological problems are now being addressed and promise to significantly advance our understanding of biology and medicine. No biological discipline will be unaffected by these technological breakthroughs.


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